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  "id": "takahashi-yamanaka-2006",
  "title": "Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors",
  "description": {
    "en": "Kazutoshi Takahashi and Shinya Yamanaka's landmark 2006 *Cell* paper (126:4) demonstrating that four transcription factors can reprogram adult cells to a pluripotent state — the discovery (Nobel Prize 2012) that founded the induced-pluripotent-stem-cell field and underlies the contemporary cellular-reprogramming longevity trajectory the corpus engages."
  },
  "authored_by": [
    "Kazutoshi Takahashi",
    "Shinya Yamanaka"
  ],
  "topics": [
    "Cellular Reprogramming",
    "Stem Cells",
    "Yamanaka Factors",
    "Longevity"
  ],
  "stance": "neutral",
  "source_type": "academic_article",
  "publish_date": "2006",
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  "follow_url": "https://www.cell.com/cell/fulltext/S0092-8674(06)00976-7"
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